The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. Selphyl® removes virtually all contaminating cells and is independent of operator technique... think of Selphyl® PRFM as the next generation PRP.
The Power of Platelets
Platelets and other components in human blood migrate to a site of injury. Platelets are known to release a variety of growth factors that respond to tissue injury, where they initiate and promote healing. By concentrating platelets at the site of injury, physicians have the potential to enhance the body’s natural capacity for healing.
Platelet Rich Plasma
Platelet Rich Plasma (PRP), by definition refers to platelets in plasma, where the platelet concentration is generally considered to be twice the normal concentration in whole blood. Red blood cells (RBC) and white blood cells (WBC) should be removed in the preparation of PRP. While some prep kits tout high platelet concentrations, they often are contaminated with RBCs or WBCs — these cells are known to have inflammatory and catabolic effects — and cause the resulting PRP to be pink in color. The ideal PRP solution will be a golden, straw-like color.
Next Generation PRP
The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood. Many PRP systems require operator skill, have varying results and level of contamination. Selphyl® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets. Think of Selphyl® PRFM as the next generation PRP.
The Selphyl® System is a completely closed system and can convert PRP to PRFM with the addition of a precise amount of calcium chloride, which initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three dimensional scaffold to maintain the platelets at the site of injection. The scaffold also serves to protect the platelets so their release of growth factors can be sustained over a longer period of time.